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This paper were supported by the Flow Cytometry Core Facility of The Cancer Institute of New Jersey (P30CA072720). We would like to express our gratitude to Dr. P. Leif Bergsagel for his critical comments and stimulating discussions on this manuscript, and for providing us the human MM cell lines used in this study. We would also like to thank Anand Desai, Jacqueline Baron, Benjamin Kreider, Will
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